2C (psychedelics)

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2C is a general name for the family of psychedelic phenethylamines containing methoxy groups on the 2 and 5 positions of the benzene ring. Most of these compounds also carry lipophilic substituents at the 4 position, usually resulting in more potent and more metabolically stable and longer acting compounds. Most of the currently known 2C compounds were first synthesized by Alexander Shulgin in the 1970's and 1980's, and published in his book, PiHKAL (Phenethylamines I Have Known And Loved). Dr. Shulgin also invented the term 2C, being an acronym for the 2 carbon atoms between the benzene ring and the amino group (the amphetamine counterparts are sometimes known as 3C's) [1].

File:2c general structure.svg
General structure of a 2C compound
Chemical structure of 2C-T-7
Chemical structure of 2C-T-21
Nomenclature R3 R4 2D Structure 3D Structure Revolving Structure
2C-B HBlank.png Br 115px 80px 100px
2C-C H Cl 115px 80px 100px
2C-D H CH3 115px 80px 100px
2C-E H CH2CH3 115px 80px 100px
2C-F H F 115px 80px 100px
2C-G CH3 CH3 115px 80px 100px
2C-G-3 (CH2)3 115px
2C-G-4 (CH2)4 115px
2C-G-N (CH)4 115px
2C-H H H 115px 80px 100px
2C-I H I 115px 80px 100px
2C-N H NO2 2C-N.png 80px 100px
2C-O H OCH3 115px 100px
2C-O-4 H OCH(CH3)2 115px 100px
2C-P H CH2CH2CH3 115px 80px 100px
2C-SE H SeCH3 115px 80px 100px
2C-T H SCH3 115px 100px
2C-T-2 H SCH2CH3 115px
2C-T-4 H SCH(CH3)2 115px 80px
2C-T-7 H S(CH2)2CH3 115px 80px
2C-T-8 H SCH2CH(CH2)2 115px 80px
2C-T-9 H SC(CH3)3 115px 80px
2C-T-13 H S(CH2)2OCH3 115px 80px
2C-T-15 H SCH(CH2)2 115px 80px
2C-T-17 H SCH(CH3)CH2CH3 115px 80px
2C-T-21 H S(CH2)2F 115px 80px
2C-TFM H CF3 115px 100px

See also


  1. Shulgin, Alexander (1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. Unknown parameter |month= ignored (help); Unknown parameter |coauthors= ignored (help)

External links

Template:2C's fi:2C