1,2-alpha-L-fucosidase

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In enzymology, a 1,2-alpha-L-fucosidase (EC 3.2.1.63) is an enzyme that catalyzes the chemical reaction

methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside + H2O L-fucose + methyl beta-D-galactoside

Thus, the two substrates of this enzyme are methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside and H2O, whereas its two products are L-fucose and methyl beta-D-galactoside.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase. Other names in common use include almond emulsin fucosidase, and alpha-(1->2)-L-fucosidase.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 2EAB, 2EAC, 2EAD, and 2EAE.

References

External links

The CAS registry number for this enzyme class is 37288-45-2.

Gene Ontology (GO) codes


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