(deoxy)nucleoside-phosphate kinase

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In enzymology, a (deoxy)nucleoside-phosphate kinase (EC is an enzyme that catalyzes the chemical reaction

ATP + deoxynucleoside phosphate Failed to parse (MathML with SVG or PNG fallback (recommended for modern browsers and accessibility tools): Invalid response ("Math extension cannot connect to Restbase.") from server "https://api.formulasearchengine.com/v1/":): \rightleftharpoons ADP + deoxynucleoside diphosphate

Thus, the two substrates of this enzyme are ATP and deoxynucleoside phosphate, whereas its two products are ADP and deoxynucleoside diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:deoxynucleoside-phosphate phosphotransferase. Other names in common use include deoxynucleoside monophosphate kinase, deoxyribonucleoside monophosphokinase, and deoxynucleoside-5'-monophosphate kinase.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1DEK and 1DEL.


External links

The CAS registry number for this enzyme class is 37278-20-9.

Gene Ontology (GO) codes