(deoxy)adenylate kinase

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In enzymology, a (deoxy)adenylate kinase (EC 2.7.4.11) is an enzyme that catalyzes the chemical reaction

ATP + dAMP ADP + dADP

Thus, the two substrates of this enzyme are ATP and dAMP, whereas its two products are ADP and dADP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)AMP phosphotransferase. This enzyme participates in purine metabolism.

References

  • IUBMB entry for 2.7.4.11
  • BRENDA references for 2.7.4.11 (Recommended.)
  • PubMed references for 2.7.4.11
  • PubMed Central references for 2.7.4.11
  • Google Scholar references for 2.7.4.11
  • Griffith TJ, Helleiner CW (1965). "The partial purification of deoxynucleoside monophosphate kinases from L cells". Biochim. Biophys. Acta. 108: 114&ndash, 24. PMID 5862227.

External links

The CAS registry number for this enzyme class is 37278-19-6.

Gene Ontology (GO) codes


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