(R)-2-haloacid dehalogenase

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In enzymology, a (R)-2-haloacid dehalogenase (EC is an enzyme that catalyzes the chemical reaction

(R)-2-haloacid + H2O (S)-2-hydroxyacid + halide

Thus, the two substrates of this enzyme are (R)-2-haloacid and H2O, whereas its two products are (S)-2-hydroxyacid and halide.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is (R)-2-haloacid halidohydrolase. Other names in common use include 2-haloalkanoic acid dehalogenase[ambiguous], 2-haloalkanoid acid halidohydrolase[ambiguous], D-2-haloacid dehalogenase, and D-DEX.


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The CAS registry number for this enzyme class is 119345-29-8.